This book explores the innovative concept of a knowledge cartridge dedicated to internal and territorial security, employing the Aitek platform - a cutting-edge AI and Big Data framework enriched by 25,000 man-days of research and development. It delves into the foundational principles of the knowledge cartridge system and subsequently addresses the critical challenges inherent in homeland and territorial security, with a particular focus on counter-terrorism efforts. Through a detailed examination, the thesis presents how artificial intelligence can be strategically applied to these challenges, offering a novel approach to enhancing security measures and operational efficiency within the domain of internal and territorial security. This work not only contributes to the academic discourse on AI's role in security but also proposes practical AI-driven solutions to complex security problems, thereby bridging the gap between theoretical research and real-world application.