The Master vampire has been destroyed, taking with him the power to lead and control the vampire population, or so the members of the Domestic Security Agency task force dedicated to destroying vampires believed. Until rumors of a trio of vampires claim to have received the power of the Master before his destruction. Alex Chance, leader of the task force's insertion team, the combat unit, has left the unit, prepared to live out his life without the constant threat of vampires. However, when his high school girlfriend, a woman he hasn't been in contact with for more than fifteen years, is attacked by one of the new Masters, he is called back to duty and takes the team to his hometown of Pine Ridge, Mississippi to findo out the truth. He learns quickly that the trio, calling themselves "The Virate," has acquired a book containing the writings of an ancient Master detailing a plan for the vampire conquest of the world. It becomes the mission of Alex Chance, known to the vampires as "The Nemesis," to find and stop them before they can claim an ancient power that will give them greater control over the vampire population and a unity that will bring about the downfall of humanity.