There have been four translations (English, Italian, Spanish and Portuguese) and thousands of copies sold of this international bestseller, written by a stress echo pioneer (i.e., according to his own definition, someone who started to work with the technique at a time when it clearly could not work). In the present third edition, the book has been enriched by contributions of an outstanding, truly international panel of experts, and encompasses the whole spectrum of applications of stress echocardiography.The content will interest both researchers and clinicians. The topics covered range from the pathophysiological basis to the economic implication; from recognition of myocardial viability to the induction of ischemia; from methodological technicalities to risk stratification strategy; from diagnosis of coronary artery disease and coronary vasospasm to the emerging applications beyond coronary artery disease in heart transplant, valvular disease and dilated cardiomyopathy.