The subject of radicals and reactive oxygen metabolites (ROMs) is complex and barely touched upon in medical schools. This title provides the ability to analyze and evaluate pathological problems arising from the chemistry of ROMs.
In recent years, the field of radical chemistry has undergone explosive growth. Although its roots lie in organic chemistry, the implications of its findings are having enormous impact in a broad range of disciplines, and we now have evidence for radical involvement in over 100 diseases. As important as this is, however, the subject of radicals and Reactive Oxygen Metabolites (ROMs) is complex and barely touched upon in the curriculum of medical schools. Reactive Oxygen Metabolites brings the subject within the grasp of even those with little preparation in chemistry. From the basic chemistry of radicals through the pathology, the author provides a clear and thorough introduction to ROMs and their importance to human health and disease.
"The author discusses the basic chemistry of reactive oxygen metabolites with great expertise and then applies this knowledge to the analysis of pathological processes. It is a treasure trove of information, but does not overwhelm and is fun to read. Due to the ever increasing importance of reactive oxygen metabolites, this text should be required reading in medical schools."
--Angel A. Roman Franco, M.D.
"?To write a single-authored, compact introductory text which encompasses all the different aspects of ROM chemistry, biology and pathology is a challenging task: the author has succeeded formidably?The text is throughout well referenced. It not only represents an easy to read overview of this complex interdisciplinary subject of biological and medical relevance, but serves also as a fountain of valuable information for more in-depth considerations. As an introductory text, this book should have wide appeal and is highly recommended. It should be a welcomed text for a special topic course at the interphase of chemistry, biology and medicine: I certainly would adopt it for my course at the advanced undergraduate and graduate level."
- Prof. Dr. W. Adam, Institut für Organische Chemie der Universität Würzburg
