This book focuses on the elucidation of the biological aspects of oxidative stress. Researchers have shown great interest in the interaction of free radicals with biological molecules ever since their discovery. As a result of successful ideas and results, oxidative stress is now acknowledged by both general and applied scientists as an advanced steady state level of reactive oxygen species with broad spectrum of biological effects. This book encompasses a broad range of issues and aspects associated with the field of oxidative stress. The relation between elimination and generation of reactive species and impact of oxidative stress have also been discussed, along with analyses of current studies on the signaling role of reactive species in eukaryotic organisms. Contemporary comprehension of homeostasis of reactive species and cellular processes has also been provided in this book for the benefit of the readers, along with valuable information for future references.